TranslatiOnal Registry for CardiomyopatHies-Plus (TORCH-Plus-DZHK21)

ID

NCT04265040

Status

Active

DZG

DZHK

Start date

08/18/2020

Parameters

Inclusion criteria
  • Non-ischemic structural cardiomyopathies Age ≥ 18 or ≤ 80 years The patient is able to understand the declaration of consent and to sign it dated At least one of the following diagnoses depending on the specific TORCH- Plus inclusion / exclusion - SOP: Dilated Cardiomyopathy (DCM) family / genetic inflammatory / persistent myocarditis idiopathic (after exclusion secondary cause) left sided systolic dysfunction (EF ≤ 45%) Left ventricular hypertrophy sarcomere hypertrophic cardiomoypathia (HCM
  • HOCM) amyloid (AL: light chains
  • TTR: transthyretin
  • wild type) Left ventricular non-compaction cardiomyopathy (LVNC) Arrhythmogenic right ventricular cardiomyopathy (ARVC / D)
Exclusion criteria
  • The following exclusion criteria have been defined and must be taken from the TORCH-Plus specific inclusion / exclusion - SOP in detail: Age: <18 years or> 80 years Patient has other (cardiac) previous illnesses: uncontrollable arterial hypertension primary pulmonary arterial hypertension radiation therapy in the chest area addiction (drug or alcohol abuse) life expectancy <1 year due to non-cardiological pre-existing conditions significant heart valve disease ischemic diseases and severe congenital heart diseases (including VSD
  • Fallot tetralogy
  • Ebstein anomaly) chemotoxic cardiomyopathy condition after myocarditis combination of several traditional risk factors (e.g. hypertension and diabetes mellitus) advanced chronic non-cardiac disease (e.g. chronic hepatitis or HIV) Tachymyopathy