Ultrasound evaluation of the inferior vena cava in addition to clinical assessment to guide decongestion in acute decompensated heart failure: a pilot study (CAVA-ADHF-DZHK10)

Status

Closed

DZG

DZHK

Start date

06/03/2017

Contact

Contacts
  • Alexander Jobs
  • Holger Thiele

Parameters

Inclusion criteria
  • Hospitalization for ADHF with dyspnea ≥NYHA III
  • peripheral edema
  • and pulmonary congestion (rales on auscultation or pulmonary vascular congestion on chest radiograph) Age ≥18 years NT-proBNP >300 ng/l within 24 h after admission Sufficient ultrasound visualization to evaluate IVC IVCmax >2.1 cm and IVCCI ≤50 % in the baseline assessment within 24 h after admission Capability to sign informed consent personally
Exclusion criteria
  • Cardiogenic shock with systolic blood pressure <90 mmHg plus end-organ hypoperfusion ADHF due to significant arrhythmias Severe pulmonary disease as primary cause of dyspnea Simplified Modification of Diet in Renal Disease estimated glomerular filtration rate <30 ml/min/1.73 m² Need for non-invasive or invasive ventilation support at baseline Pregnancy Participation in another interventional trial regarding heart failure treatment