Registry entries
- Gerd Hasenfuß
- Rolf Wachter
- Frank Edelmann
Systolic dysfunction to congestive heart failure cohort study (TransitionCHF-DZHK2)
Contact
Contacts
Parameters
Inclusion criteria
- Asymptomatic systolic dysfunction (defined as: ejection fraction < 40% by echocardiography or MRI
- documented within the last 3 months prior to baseline visit) No history of hospitalization for heart failure (defined as hospitalisation with symptoms of heart failure requiring initiation of therapy with a loop diuretic or escalation of a pre-existing loop diuretic therapy within 48 hours after hospital admission) No heart failure symptoms (NYHA II
- III or IV) upon inclusion 6MWD ≥ 80% of reference values Written informed consent Age ≥ 18 years
- Symptomatic heart failure (NYHA>I) at baseline visit Any significant valvular disease (> 2nd degree) Severe pulmonary disease (e. g. FEV1 < 70% of normal limit) Severe renal disease (GFR < 15 ml/min) ejection fraction at baseline visit ≥ 50% by echocardiography or MRI Life expectancy < 1 year Pericardial disease Hypertrophic cardiomyopathy Myocardial infarction within the last 3 months Planned cardiac surgical intervention within 3 months after inclusion Geographical reasons (e. g. patients living outside Germany or planning to move abroad) Inability to give informed consent (e. g. mental disorders) Therapy with loop diuretics (e. g. torasemide
- furosemide
- piretanide)